From MS Exchange 2013 Mailbox Server Security Technical Implementation Guide
Part of SRG-APP-000246
Associated with: CCI-001094
Mail quota settings control the maximum sizes of a user’s mailbox and the system’s response if these limits are exceeded. Mailbox data that is not monitored against a quota increases the risk of mail loss due to filled disk space, which can also render the system unavailable. There are multiple controls, which supply graduated levels of opportunity to respond before risking email service loss. 
Review the Email Domain Security Plan (EDSP). Determine the value for Prohibit Send Quota Limit. Open the Exchange Management Shell and enter the following command: Get-MailboxDatabase | Select Name, Identity, ProhibitSendQuota If the value of ProhibitSendQuota is not set to the site's Prohibit Send Quota Limit, this is a finding.
Update the EDSP.
Open the Exchange Management Shell and enter the following command:
Set-MailboxDatabase  -Identity <'IdentityName'> -ProhibitSendQuota <'QuotaLimit'>
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